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Research Article | Volume 11 Issue 2 (Feb, 2025) | Pages 312 - 314
Case Study Of 100 Cases of Chronic Cervical Lymphadenopathy
 ,
 ,
1
Consultant, Barmeda Surgical hospital, Junagadh; Ex-Associate Professor, Department of General Surgery, M P Shah Medical College, Jamnagar, Gujarat, India
2
Third year resident, Department of General Surgery, B J Medical College and Civil Hospital, Ahmedabad, Gujarat, India
3
Associate Professor, Department of General Surgery, B J Medical College and Civil Hospital, Ahmedabad, Gujarat, India
Under a Creative Commons license
Open Access
Received
Dec. 9, 2024
Revised
Jan. 11, 2025
Accepted
Jan. 15, 2025
Published
Feb. 19, 2025
Abstract

Chronic cervical lymphadenopathy (CCL) is a prevalent clinical concern, often posing diagnostic challenges due to its diverse etiologies. This study retrospectively examines 100 cases of CCL to delineate their clinical presentations, diagnostic approaches, and underlying causes. Most common etiological factor was tubercular lymphadenitis, which affects younger age group, confirm by histopathological examination and management is Anti-tubercular treatment. These findings underscore the importance of a thorough clinical evaluation and the utility of FNAC in the diagnostic workup of CCL, particularly in regions with a high prevalence of TB. Early and accurate diagnosis is crucial for effective management and improved patient outcomes.

Keywords
INTRODUCTION

The chronic cervical lymphadenopathy is common neck swelling among this tuberculous lymphadenopathy is most common in India. Secondary metastasis is common in elderly patients. Mainly because of prevalence of tuberculous in our country, a majority of patients empirically put on anti-tubercular therapy without FNAC or histopathological diagnosis and in the absence of proper treatment hazards. While considering the differential diagnosis our main aim to find out if swelling is inflammatory or malignant and if inflammatory whether it is tuberculous or not. In young adults, common causes are tuberculosis and lymphoma.

 

AIMS AND OBJECTIVES

  1. To analyze the etiological factors of chronic cervical lymphadenopathy.
  2. To analyze the age and sex distribution of chronic cervical lymphadenopathy.
  3. To correlate clinical diagnosis with FNAC and histopathological diagnosis.
  4. To authenticate the importance of clinical diagnosis.
MATERIALS AND METHODS

Study type: Randomized prospective study

Study site: Department of General Surgery, Guru Gobind Singh Hospital Jamnagar

Study Duration: January 2002 to November 2003

 

INCLUSION CRITERIA-

Age of patient more than 12 years.

Study includes patients presenting with discrete cervical lymphadenopathy of greater than 4-week duration.

 

Consent to participate in study.

 

EXCLUSION CRITERIA-

Age less than 12 years (in this group chronic cervical lymphadenopathy is mostly due to scalp lesions, lice etc.)

Lymph nodes less than 10 mm in size (clinically insignificant)

Non-compliant patient.

RESULTS

A clinical study of 100 cases of chronic cervical lymphadenopathy admitted in various department or outpatient department of Guru Gobind Singh Hospital Jamnagar from January 2002 to November 2003 was done.

 

TABLE 1- ETIOLOGICAL DISTRIBUTION

 

Cases

Tuberculous

47

Hodgkins’s lymphoma

08

Non-Hodgkins lymphoma

03

Metastasis

27

Non specific

11

Others

04

Total

100

 

TABLE 2- AGE DISTRIBUTION

AGE

MALE

FEMALE

TB

HODGKINS

NS

NHL

METASTASIS

OTHERS

TB

HODGKINS

NS

NHL

METASTASIS

OTHERS

Total

12-20

06

03

04

01

00

00

13

01

01

01

00

00

30

21-40

14

02

04

00

04

01

07

00

01

00

04

02

39

>40

03

01

01

01

16

01

04

01

00

00

03

00

31

Total

23

06

09

02

20

02

24

02

02

01

07

02

100

TB - Tuberculosis; NS - Nonspecific; NHL - Non Hodgkins lymphoma

 

TABLE 3- SEX DISTRIBUTION

 

MALE

FEMALE

TOTAL

Tuberculosis

23

24

47

Hodgkins

06

02

08

Non-Hodgkins

02

01

03

Non specific

09

02

11

Metastatic

20

07

27

Others

02

02

04

 

62

38

100

 

TABLE 4- PERCENTAGE DISTRIBUTION OF TB / NON TB CASES

Age (years)

Total cases

% of TB cases

% of non-TB cases

12-20

30

63.33

36.66

21-40

39

53.84

46.15

>40

31

22.58

77.41

 

TABLE 5- CORRELATION BETWEEN CLINICAL DIAGNOSIS AND HISTOPATHOLOGICAL DIAGNOSIS

 

No of cases

percentage

True clinical diagnosis

73

73%

False clinical diagnosis

27

27%

 

TABLE 6- CORRELATION BETWEEN FNAC AND INCISIONAL EXCISIONAL

 

NO of cases

percentage

True positive FNAC

68

68%

False negative FNAC

32

32%

DISCUSSION

A total of 100 patients were included in this study. The various causes for cervical lymphadenopathy as found are shown in Table-1. Out of 100 cases 47% cases found to have tuberculous cervical lymphadenopathy. It is evident from Table-1 that tuberculosis is the most common cause of cervical lymphadenopathy.

 

Their sex distribution is shown in Table-3. There were 62 males and females. The male to female (M:F) ratio was found to be 1:1.09. The maximum number of cases was found to be in the age group of 12 to 20 (63%)

 

During study correlation was made between clinical diagnosis and histopathological diagnosis. In 73% cases clinical diagnosis was true and correlated with histopathological diagnosis. In 27 cases there was fallacies in clinical diagnosis. FNAC was able to diagnosis (truly) in 68% cases.

 

From above discussion it is evident that in all chronic cervical lymphadenopathy patients histopathological diagnosis should be done and patient should not be put on empirical anti-Koch’s treatment without histopathological diagnosis. Role of FNAC is limited in our setup due to lack of expert cytopathologist. Anti-Koch’s treatment should not be started without HP examination.

CONCLUSION
  1. Most common etiological factor was tuberculous lymphadenitis.
  2. Age group involved suggests between 21-40 years maximum affected.
  3. Sex distribution suggest male predominance.
  4. Clinical diagnosis was true in 73% cases.
  5. Fallacies in clinical diagnosis was in 27% cases.
  6. FNAC is not reliable in our set up due to lack of expert cytologist and all patients requires histopathological HP examination.
  7. Most common form of management was anti-Koch’s treatment.

Patients with chronic lymphadenopathy should not be put empirically on anti Koch’s treatment without histopathological diagnosis.

REFERENCES
  1. History : short practice of surgery. 28th Bailey and Love’s
  2. Surgical anatomy : Lee McGregor’s
  3. Short cases in surgery. S. K. Bhattacharya
  4. Chronic cervical lymphadenopathy : P. K. Jhawer, D. Bharat and M. M. Begani. Indian Journal Surgery. 1990
  5. Gupta AK, gupta SC, Singh DR et al. : Lymphadenopathy – a clinicohistological evaluation. Indian journal surgery. 1998,50
  6. Pranshu Bhargava, Ajay Kumar Jain et al. : Chronic cervical lymphadenopathy. Indian journal of Surgery. 2002 : 64
  7. Anjali Dasgupta, RN Ghosh, AK Mitra, G. Gupta et al. : FNAC of cervical lymphadenopathy with special reference to TB. Indian Med. Assoc. 1994
  8. Young AE. The neck.In New Aird’s Companion in Surgical Studed 3rd Burnand Kevin G. Young Anthony E, London, Churchill Livingstone, 1998
  9. Sarda AK, Bal S, Singh MK, et al’. Fine needle aspiration cytology as a preliminary diagnosis procedure for asymptomatic cervical lymphadenopathy J Assoc Physician India 1990
  10. Misra SD, GargBK. Cervical lymphadenopathy in children A study of 137 cases. Indian Pediatrics 1972
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